Functional disorders as a common motor manifestation of COVID-19 infection or vaccinationArticle Published on 2023-03-012023-07-10 Journal: European journal of neurology [Category] COVID19(2023년), [키워드] COVID-19 functional Movement disorders SARS-CoV-2 vaccine. [DOI] 10.1111/ene.15630 PMC 바로가기
An integrated metabolomic and proteomic approach for the identification of covalent inhibitors of the main protease (Mpro) of SARS-COV-2 from crude natural extractsArticle Published on 2023-01-152022-11-15 Journal: Talanta [Category] SARS, 유전자 메커니즘, 치료제, [키워드] Analysis applied approach baicalein binding carried catalytic characteristic Chinese complementary complex Compound Covalent binder Cys145 database drug target electrophilic Final functional HIS163 HIS164 His41 independent inhibitor inhibitors Ion knowledge M pro M(pro) mass mass spectrometry maturation metabolomic metabolomics Michael molecular dynamics MPro nucleophilic peptide platform polyprotein protease protein-ligand Proteins proteomic proteomics residue SARS-CoV-2 SARS-CoV-2. Scutellaria baicalensis tested the SARS-CoV-2 [DOI] 10.1016/j.talanta.2022.123824 PMC 바로가기
Electrochemical paper-based antigen sensing platform using plant-derived monoclonal antibody for detecting SARS-CoV-2Article Published on 2023-01-012022-11-15 Journal: Talanta [Category] SARS, 진단, 치료기술, 치료제, [키워드] anti-SARS-CoV-2 antibody Antigen applicability applied approach Cellulose Concentration COVID-19 diagnosis CR3022 detect diagnostic Differential pulse voltammetry expressed functional group limit of detection linear relationship monoclonal antibody nasopharyngeal swab sample Nicotiana benthamiana Paper-based electrochemical immunosensor Plant-based antibody platform point-of-care pulse quantification RBD Receptor binding domain Saliva SAR-CoV-2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2. Spike protein the RBD this system was performed [DOI] 10.1016/j.talanta.2022.123783 PMC 바로가기
What are the long-term holistic health consequences of COVID-19 among survivors? An umbrella systematic reviewArticle Published on 2022-12-012022-11-16 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, [키워드] acute COVID-19 acute phase acute respiratory syndrome affected conducted consequence coronavirus COVID-19 COVID-19 treatments demographic data determine eligibility criteria employment Epidemiology fatigue functional Health Impact individual Laboratory parameters memory Pandemics Participants physical Psychological psychological impacts Quality of life ranged Research respiratory symptoms Sample SARS Coronavirus screened survived Survivors systematic review systematic reviews variant virus virus classification. [DOI] 10.1002/jmv.28086 PMC 바로가기
Who complies with prevention guidelines during the fourth wave of COVID-19 in Italy? An empirical studyResearch article Published on 2022-12-012022-10-05 Journal: Personality and Individual Differences [Category] 변종, [키워드] Affect association carried Compliance COVID-19 cross-sectional design dark Dark Triad disease Factor fear functional healthy implication include Italy measure Moderation narcissism pandemic participant Personality positive prevention Protective protective behaviour public health reduce Research Result social distancing Spread the SARS-CoV-2 vaccination variety virus washing hands wearing masks [DOI] 10.1016/j.paid.2022.111845 [Article Type] Research article
Genomic variants-driven drug repurposing for tuberculosis by utilizing the established bioinformatic-based approachShort communication Published on 2022-12-012022-10-05 Journal: Biochemistry and Biophysics Reports [Category] 신약개발, [키워드] annotations applied approach bioinformatics biological process CCR5 CD44 cellular component contribute CXCR4 demonstrated deregulation disease disease-associated drug Drug discovery Drug repurposing drug target evaluated Evidence facilitate functional functional annotation Genes genomic genomic variant genomic variants GWAS HLA-B identify implementation in-silico indication involved KEGG Missense mutation molecular overlapped Pathogenesis Pathway analysis provided risk SELP suggested target Treatment Tuberculosis variant [DOI] 10.1016/j.bbrep.2022.101334 [Article Type] Short communication
Epistasis-Driven Evolution of the SARS-CoV-2 Secondary StructureArticle Published on 2022-12-012022-11-16 Journal: Journal of molecular evolution [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome arises arising base pairs Compensatory Compensatory evolution conserved coronavirus Deleterious derived allele epistasis Evolution form Frequency functional genetic background Genome highlight Hydrogen bond Hypothesis Last Modification motif Mutation natural selection pathogenicity regulate RNA SARS-CoV-2 secondary secondary structure Secondary structure. Structure target the SARS-CoV-2 UTR viral replication [DOI] 10.1007/s00239-022-10073-1 PMC 바로가기
Evaluation of degradation performance toward antiviral drug ribavirin using advanced oxidation process and its relations to ecotoxicity evolutionResearch article Published on 2022-12-012022-10-05 Journal: The Science of the total environment [Category] 치료제, [키워드] addition Analysis antiviral drug antiviral drugs applied conditions coronavirus disease Degradation discharged ecosystem Ecotoxicity evaluation effort eliminated Evolution functional Health identify investigated liquid Quantitative ribavirin risk Spread Stage Toxicity Transformation products treated Treatment UV/TiO2/H2O2 process Wastewater treatment [DOI] 10.1016/j.scitotenv.2022.157851 [Article Type] Research article
The prominent role of a CDR1 somatic hypermutation for convergent IGHV3-53/3-66 antibodies in binding to SARS-CoV-2SARS-CoV-2에 결합하는 수렴형 IGHV3-53/3-66 항체에 대한 CDR1 체세포 과돌연변이의 두드러진 역할Article Published on 2022-12-012022-09-12 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 진단, [키워드] acute respiratory syndrome Analysis antibodies antibody antibody affinity binding binding affinity Cdr1 contributed Coronavirus-2 COVID-19 Frequency functional germline gene Humoral immunity IGHV3-53/3-66 knowledge mAb mAbs monoclonal monoclonal antibody Mutation other coronaviruses SARS-CoV-2 somatic hypermutation. somatic hypermutations Treatment [DOI] 10.1080/22221751.2022.2063074 PMC 바로가기 [Article Type] Article
Non-uniform aspects of the SARS-CoV-2 intraspecies evolution reopen question of its originArticle Published on 2022-12-012022-11-16 Journal: International journal of biological macromolecules [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] acute respiratory syndrome beta-coronavirus Characteristics conducted conserved coronavirus disease Coronavirus-2 COVID-19 distribution Evenly-uneven Evidence Evolution Frequency functional furin cleavage Furin cleavage site (FCS) hypothese Hypothesis Invariant regions Mutation mutations pandemic Pandemics Protein question Region residue residues SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2. Support the SARS-CoV-2 Transmissibility unique variants virulence virus [DOI] 10.1016/j.ijbiomac.2022.09.184 PMC 바로가기